Eric Bouffet Selected Research

Brain Stem Neoplasms (Brain Stem Tumor)

1/2022	Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.
1/2020	Indolent course of brainstem tumors with K27M-H3.3 mutation.
4/2012	Favorable outcome with conservative treatment for children with low grade brainstem tumors.
3/2011	Diffuse intrinsic brainstem tumor in an infant: a case of therapeutic efficacy with vinorelbine.
9/2010	Patterns of enrollment of infants with central nervous system tumours on cooperative group studies: a report from the Canadian Pediatric Brain Tumour Consortium.
3/2010	Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets.

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Eric Bouffet Research Topics

Disease

119	Neoplasms (Cancer) 01/2022 - 12/2003
52	Medulloblastoma 10/2022 - 09/2003
47	Glioma (Gliomas) 03/2022 - 06/2005
30	Brain Neoplasms (Brain Tumor) 10/2021 - 09/2002
22	Diffuse Intrinsic Pontine Glioma 01/2022 - 02/2008
16	Ependymoma 01/2022 - 04/2006
13	Astrocytoma (Pilocytic Astrocytoma) 05/2020 - 01/2008
11	Germinoma 01/2022 - 06/2006
9	Hydrocephalus (Hydrocephaly) 12/2021 - 04/2005
7	Glioblastoma (Glioblastoma Multiforme) 11/2021 - 01/2008
7	Central Nervous System Neoplasms 01/2021 - 01/2008
6	Brain Stem Neoplasms (Brain Stem Tumor) 01/2022 - 03/2010
6	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 09/2020 - 04/2010
5	Choroid Plexus Papilloma 10/2021 - 04/2010
5	Disease Progression 10/2021 - 06/2005
5	Primitive Neuroectodermal Tumors (PNET) 08/2014 - 09/2003
4	Hearing Loss (Hearing Impairment) 12/2021 - 06/2014
4	Turcot syndrome 01/2021 - 01/2016
4	Neoplasm Metastasis (Metastasis) 01/2021 - 11/2013
4	Craniopharyngioma (Craniopharyngiomas) 11/2020 - 05/2007
4	Ototoxicity 09/2020 - 05/2005
4	Hypersensitivity (Allergy) 01/2019 - 06/2005
4	Choroid Plexus Carcinoma 01/2019 - 06/2010
3	Tuberous Sclerosis (Bourneville's Disease) 05/2020 - 03/2010
3	Pinealoma (Pineoblastoma) 01/2020 - 01/2020
3	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 01/2019 - 02/2011
3	Infratentorial Neoplasms (Posterior Fossa Tumors) 01/2018 - 06/2011
3	Cognitive Dysfunction 01/2018 - 07/2010
3	Sarcoma (Soft Tissue Sarcoma) 11/2017 - 12/2003
2	Teratoma (Teratoid Tumor) 11/2022 - 05/2020
2	Ascites 03/2022 - 11/2016
2	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2022 - 02/2008
2	Neurofibromatoses (Neurofibromatosis) 01/2022 - 06/2012
2	Rhabdomyosarcoma 01/2022 - 03/2010
2	Microsatellite Instability 01/2021 - 11/2017
2	Carcinogenesis 12/2020 - 10/2020
2	Typical Teratoid Rhabdoid Tumor 10/2020 - 01/2019
2	Diabetes Insipidus 01/2020 - 05/2010
2	Rhabdoid Tumor (Rhabdoid Tumors) 01/2019 - 07/2010
2	Neutropenia 01/2019 - 08/2011
2	Death (Near-Death Experience) 05/2018 - 01/2016
2	Carcinoma (Carcinomatosis) 08/2015 - 01/2015
2	Hemorrhage 05/2015 - 02/2011
2	Chronic Disease (Chronic Diseases) 01/2015 - 09/2006

Drug/Important Bio-Agent (IBA)

24	dipinacoline glutamateIBA 01/2022 - 02/2008
22	Biological ProductsIBA 03/2021 - 11/2004
9	Carboplatin (JM8)FDA LinkGeneric 12/2021 - 06/2005
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2009
7	MicroRNAs (MicroRNA)IBA 01/2021 - 12/2009
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2005
7	Vinblastine (Vinblastine Sulfate)FDA Link 01/2019 - 06/2005
6	Etoposide (VP 16)FDA LinkGeneric 01/2022 - 07/2006
6	Cisplatin (Platino)FDA LinkGeneric 09/2020 - 05/2010
6	Pharmaceutical PreparationsIBA 01/2020 - 06/2010
6	Temozolomide (Temodar)FDA LinkGeneric 01/2018 - 07/2006
5	Vincristine (Oncovin)FDA LinkGeneric 01/2022 - 03/2010
5	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2019 - 04/2010
5	Formaldehyde (Formol)FDA Link 01/2016 - 04/2011
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 01/2018
4	Bevacizumab (Avastin)FDA Link 07/2020 - 05/2015
4	Mitogen-Activated Protein KinasesIBA 01/2020 - 01/2017
4	ParaffinIBA 01/2016 - 04/2012
3	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2016
3	ErbB Receptors (EGF Receptor)IBA 01/2022 - 11/2009
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 05/2007
3	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2021 - 03/2015
3	trametinibIBA 12/2020 - 01/2018
3	trans-sodium crocetinate (crocetin)IBA 05/2020 - 03/2010
3	Phosphotransferases (Kinase)IBA 01/2019 - 05/2008
3	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2019 - 02/2011
3	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2019 - 02/2011
3	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2014 - 02/2006
3	Histones (Histone)IBA 10/2014 - 09/2012
2	AZD 6244IBA 01/2022 - 01/2019
2	RNA (Ribonucleic Acid)IBA 11/2020 - 01/2020
2	TOR Serine-Threonine KinasesIBA 05/2020 - 01/2019
2	Tumor Biomarkers (Tumor Markers)IBA 05/2020 - 06/2006
2	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 01/2020 - 01/2015
2	Sirolimus (Rapamycin)FDA Link 01/2020 - 03/2010
2	dabrafenibIBA 12/2019 - 12/2019
2	tyrosine receptor (receptor, tyrosine)IBA 01/2019 - 05/2008
2	ChromatinIBA 01/2018 - 08/2012
2	Lomustine (CCNU)FDA Link 03/2016 - 09/2002
2	AlkaloidsIBA 01/2015 - 03/2011
2	Vinorelbine (Navelbine)FDA LinkGeneric 01/2015 - 03/2011
2	nimotuzumabIBA 11/2014 - 11/2009

Therapy/Procedure

75	Therapeutics 11/2022 - 12/2003
72	Drug Therapy (Chemotherapy) 03/2022 - 09/2003
52	Radiotherapy 10/2022 - 09/2003
14	Craniospinal Irradiation 10/2022 - 01/2012
8	Re-Irradiation 01/2021 - 08/2012
4	Immunotherapy 01/2022 - 12/2020
4	Aftercare (After-Treatment) 11/2020 - 12/2011
4	Palliative Care (Palliative Therapy) 01/2020 - 11/2011
3	Adjuvant Chemotherapy 10/2022 - 04/2014
3	Stem Cell Transplantation 10/2021 - 01/2019
3	Chemoradiotherapy 01/2020 - 05/2005
3	Terminal Care (Care, Terminal) 05/2018 - 07/2006
3	Craniotomy 10/2013 - 07/2004
2	Neoadjuvant Therapy 08/2015 - 08/2015